“Scientists Tackle Virus Naming Chaos Amid Dengue Surge in 2024”


Viruses have long been named based on the places or animals where they were first discovered. However, the scientific community is now making concerted efforts to bring more order and consistency to the process of virus naming. This initiative aims to address the chaos and confusion that often surrounds viral nomenclature, making it easier for researchers to identify, classify, and study these pathogens.

In the late 16th century, outbreaks of a strange new disease were reported in various parts of the world, including Philadelphia, Puerto Rico, Java, and Cairo. The illness, characterized by fever and severe body pain, was initially referred to as “break-bone fever” or “quebranta huesos” in Latin America. This disease would later be recognized as dengue fever, a name that offers a glimpse into the often intriguing and random world of virus naming.

The History and Evolution of Dengue Fever

Early Observations and Naming

In 1801, an outbreak of the disease in Madrid affected Queen María Luisa de Parma of Spain. In a letter she wrote during her recovery, the Queen referred to the illness by a name that we recognize today: dengue. “I’m feeling better, because it has been the cold in fashion, that they call dengue,” she wrote. This marked one of the earliest documented uses of the term.

We now understand that dengue fever is caused by four closely related viruses within the flavivirus group. These viruses are transmitted by specific species of mosquitoes, particularly Aedes aegypti and Aedes albopictus, which thrive in tropical and subtropical regions. The disease can spread rapidly in areas where these mosquitoes are prevalent, leading to significant outbreaks.

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Recent Statistics and Trends

In the first four months of 2024, over 7.6 million cases of dengue and 3,000 deaths were reported to the World Health Organization (WHO). This surpassed the 6.5 million cases reported for the entire year of 2023. By July 2024, the WHO had recorded 9.6 million cases and 5,366 deaths globally, marking the highest incidence on record. The surge in cases has been attributed to factors such as climate change and the El Niño climate pattern, which create warmer, wetter conditions conducive to mosquito proliferation.

In 2024, dengue was actively transmitting in 90 countries, with 31 of them reporting higher-than-usual case numbers. The Americas saw the most significant increase, prompting the Centers for Disease Control and Prevention (CDC) to issue a health alert about the heightened risk of dengue virus infections in the United States.

The Intriguing World of Virus Naming

Naming Based on Symptoms and Locations

The story of dengue’s name sheds light on the fascinating and often haphazard world of virus naming. Many viruses derive their names from their symptoms, while others are named after the locations or animals where they were first identified. For instance, dengue might be derived from the Spanish version of a Swahili term, “ki denga pepo,” meaning a sudden onset by an evil spirit. Alternatively, it could come from the Caribbean pronunciation of “dandy” or the Spanish “dengeruo,” referring to the stiff, awkward gait of those afflicted.

Virus Classification Today

As of now, there are 14,690 officially classified virus species, but scientists believe this number only scratches the surface. Mammals alone are estimated to harbor around 320,000 viruses. A recent study of the human gut identified 140,000 bacteriophages, a type of virus that infects bacterial cells. Approximately 270 viruses are known to infect humans, with new ones emerging regularly, such as Sars-CoV-2, Zika virus, and Mpox.

The Science Behind Naming and Classifying Viruses

Modern Techniques and Systems

Advances in analytical techniques have made it easier to identify and classify viruses, leading to a rapid expansion in the list of known viruses. Scientists are now developing systematic naming systems to bring order to this growing chaos. These systems help in identifying and categorizing new viruses as they emerge, facilitating research and public health responses.

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The Role of the International Committee on Taxonomy of Viruses (ICTV)

The ICTV is the body responsible for maintaining the list of viruses with approved names. Advances in genetic sequencing technology have equipped scientists to better determine whether viruses are related. For example, viral hemorrhagic fevers (VHFs) can be caused by four distinct families of viruses, grouped based on their genetic makeup.

The Naming of Viral Hemorrhagic Fevers

Symptom-Based Naming

Viral hemorrhagic fevers, including dengue, often derive their names from their symptoms. Another mosquito-borne VHF affecting the liver and causing jaundice is aptly named Yellow Fever. However, symptom-based naming can be problematic, as other infections with similar symptoms can cause confusion. For instance, several liver infections, such as Hepatitis A, B, C, D, and E, can also lead to jaundice.

Geographic-Based Naming

Some viruses are named after the locations where they were first identified. For example, the Machupo Virus, responsible for Bolivian Hemorrhagic Fever, is named after a river in Bolivia. Interestingly, some viruses have been named after two different places. Crimean-Congo Hemorrhagic Fever (CCHF) is an example, named after regions in Crimea and the Congo where the virus was identified.

The Role of Technology in Virus Identification

Advances in Microscopy and Genetic Sequencing

The 20th century saw significant advances in microscopy, enhancing the ability to detect and identify viruses. The advent of the electron microscope allowed for the discovery of many significant viruses, including Hepatitis B in 1970. In the 21st century, rapid sequencing of viral genetic material has become a crucial tool. Whole-genome sequencing technologies can now identify unknown viral sequences, as demonstrated when scientists in Wuhan identified Sars-CoV-2 in 2019.

The Baltimore Classification System

The Baltimore Classification System, developed by virologist David Baltimore, categorizes viruses based on their genetic material. This system includes seven groups, ranging from double-stranded DNA viruses to single-stranded RNA viruses. This classification helps in understanding the biological relationships between viruses, aiding in the development of diagnostic tests and antiviral treatments.

The ICTV and Modern Virus Taxonomy

The Need for a Systematic Approach

The ICTV categorizes viruses into Realms, Orders, and Families, similar to the Linnean method used in biological taxonomy. For example, the Dengue virus belongs to the Flaviviridae family and the Flavivirus genus. In contrast, Chikungunya belongs to the Togaviridae family and the Alphavirus genus. This systematic approach helps virologists communicate effectively and collaborate on a global scale.

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The Challenges and Future Directions

Next-generation genetic sequencing technologies are rapidly increasing the number of known viruses. The ICTV’s catalog now includes nearly 15,000 viruses, and this number is expected to grow. Most known viruses do not cause diseases, but those that do are often given recognizable names in addition to their official designations. Ensuring effective communication among scientists worldwide remains a priority, especially during global health crises like the Covid-19 pandemic.


What is the origin of the name dengue?

The exact origin of the name dengue is uncertain. It might be derived from a Spanish version of a Swahili term, “ki denga pepo,” meaning a sudden onset by an evil spirit. Alternatively, it could come from the Caribbean pronunciation of “dandy” or the Spanish “dengeruo,” referring to the stiff, awkward gait of those afflicted.

How many viruses are known to infect humans?

Approximately 270 viruses are known to infect humans, but this number is continually growing with the emergence of new infectious diseases.

What role does the ICTV play in virus naming?

The International Committee on Taxonomy of Viruses (ICTV) maintains the list of viruses with approved names and categorizes them into Realms, Orders, and Families. The ICTV also settles disputes about naming and ensures effective communication among scientists.

How has technology advanced virus identification?

Advances in microscopy and genetic sequencing have significantly enhanced the ability to detect and identify viruses. Whole-genome sequencing technologies can identify unknown viral sequences, as demonstrated during the identification of Sars-CoV-2 in 2019.

Why is systematic virus naming important?

Systematic virus naming is crucial for understanding biological relationships, developing diagnostic tests, and creating antiviral treatments. It also aids in predicting the behavior of emerging viruses and assists in vaccine development.


The evolving science of virus naming and classification is essential for effective research and public health responses. From the intriguing origins of names like dengue to the systematic efforts of the ICTV, the field of virology continues to advance rapidly. As new technologies emerge and the number of known viruses grows, maintaining a structured and logical approach to naming and classification will be more important than ever. This ensures that scientists worldwide can communicate effectively and collaborate to address global health challenges.

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